Hyperpolarized MR Imaging
Enhanced NMR signals attainable with 13C, 15N, 29Si and 31P nuclei have the potential to study cellular metabolism, NMR of complex bio-mixtures, metabolic kinetic studies.
Instrumentation for PHIP, including a para-hydrogen generator (Bruker BioSpin), a PC-controlled Field Cycling system and a low field MR spectrometer for field cycling (Stelar), is available at the University of Torino, while Pisa (University of Pisa and FTGM) hosts a DNP Hypersense Polarizer (Oxford Instr.).
Hyperpolarized agents can be prepared and tested on-site in vitro and/or in animal models.