Photoacustic imaging (PA) integrates the sensitivity of optical imaging with the resolution of high-frequency ultrasound, to provide insights into tissue microenvironment and hemodynamic changes, addressing the needs of different biological research areas. This hybrid imaging modality is able to detect and quantify endogenous photoacoustic signals of oxy- and deoxy-hemoglobin, as well as photoacoustic contrast agents like gold nanorods and carbon nanotubes that have emerged in recent years as specific and customizable agents for cancer detection and marking of genetic mutations cancer-associated, improving early detection and treatment of neoplasias.
Available at the centre for Preclinical Imaging in Colleretto Giacosa, at IFC-CNR in Pisa and at IBB-CNR in Naples.
LOIS 3D combines light and sound to produce a three dimensional image of tissue-simulating phantoms, small animals, and other types of tissue submerged in the imaging module. LOIS-3D is the first system of its kind to produce comprehensive information based upon volumetric optoacoustic tomography depicting the absorbed optical energy (blood distribution and its oxygenation). This provides an extremely rich set of complementary anatomical and functional 3D images.
Available at the University of Torino, Torino.