Research activity: projects and publications

UNITO - Selected publications and grants from last 5 years

  1. Di Gregorio, Enza; Lattuada, Luciano; Maiocchi, Alessandro; Aime, Silvio; Ferrauto, Giuseppe; Gianolio, Eliana “Supramolecular adducts between macrocyclic Gd(iii) complexes and polyaromatic systems: a route to enhance the relaxivity through the formation of hydrophobic interactions” CHEMICAL SCIENCE  2021, DOI 10.1039/D0SC03504A
  2. Baroni, Simona; Stefania, Rachele; Broche, Lionel M; Senn, Nicholas; Lurie, David J; Ross, P James; Aime, Silvio; Geninatti Crich, Simonetta “A Novel Class of 1 H-MRI Contrast Agents Based on the Relaxation Enhancement Induced on Water Protons by 14 N-Containing Imidazole Moieties” ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 2020, 59, 2, DOI 10.1002/anie.202011513
  3. Tripepi M.; Ferrauto G.; Bennardi P.O.; Aime S.; Delli Castelli D. “Multilamellar LipoCEST Agents Obtained from Osmotic Shrinkage of Paramagnetically Loaded Giant Unilamellar Vescicles (GUVs)” ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 2020, DOI 10.1002/anie.201912327
  4. Eills J.; Cavallari E.; Carrera C.; Budker D.; Aime S.; Reineri F. “Real-Time Nuclear Magnetic Resonance Detection of Fumarase Activity Using Parahydrogen-Hyperpolarized [1-13C]Fumarate” JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2019, 141,20209, DOI 10.1021/jacs.9b10094
  5. Alberti D, Deagostino A, Toppino A, Protti N, Bortolussi S, Altieri S, Aime S, Geninatti Crich S. “An innovative therapeutic approach for malignant mesothelioma treatment based on the use of Gd/boron multimodal probes for MRI guided BNCT” JOURNAL OF CONTROLLED RELEASE  2018, 280, 31, DOI 10.1016/j.jconrel.2018.04.043
  6. Ferrauto G, Di Gregorio E, Ruzza M, Catanzaro V, Padovan S, Aime S. “Enzyme-Responsive LipoCEST Agents: Assessment of MMP-2 Activity by Measuring the Intra-liposomal Water 1 H NMR Shift” ANGEWANDTE CHEMIE. INTERNATIONAL EDITION  2017, 56, 12170,DOI 10.1002/anie.201706271
  7. Geninatti Crich S, Terreno E, Aime S. “Nano-sized and other improved reporters for magnetic resonance imaging of angiogenesis”, Adv Drug Deliv Rev 2017, 119, 61-72
  8. Longo DL, Stefania R, Callari C, De Rose F, Rolle R, Conti L, Consolino L, Arena F, Aime S.” Water Soluble Melanin Derivatives for Dynamic Contrast Enhanced  Photoacoustic Imaging of Tumor Vasculature and Response to Antiangiogenic Therapy”,  Adv Health Mater. 2017, 6(1)
  9. Hu H, Arena F, Gianolio E, Boffa C, Di Gregorio E, Stefania R, Orio L, Baroni S, Aime S. “Mesoporous silica nanoparticles functionalized with fluorescent and MRI reporters for the visualization of murine tumors overexpressing αvβ3 receptors”, Nanoscale. 2016, 8(13):7094-104
  10. Longo DL, Arena F, Consolino L, Minazzi P, Geninatti-Crich S, Giovenzana GB,  Aime S. “Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners. Biomaterials”, 2016, 75:47-57
  • H2020-PHC-2015 project: “In Vivo Spectral Photon Counting CT Molecular Imaging in Cardio- and Neuro-Vascular Diseases - SPCCT” (2016-2021)
  • PON MOLIM ONCOBRAIN “Molecular imaging Innovative methods for the study of tumor and neurodegenerative pathologies” (MOLIM OncoBrain)”, 2018-2021
  • H2020-INFRAEOSC-2018: “Providing an open collaborative space for digital biology in Europe” (EOSC-Life), 2019-2023
  • H2020-FETOPEN-2018-2019-2020-01: “NEutron Capture-enhanced Treatment of neurotoxic Amyloid aggRegates” (NECTAR), 2021-2024.
  • National Project AIRC: “An innovative Neutron Capture Therapy approach for the treatment of Mesothelioma and diffused thoracic tumour” (2020-2025)
  • H2020 FETOPEN RIA: “Prepolarized MRI at Earth Field to seek new contrasts linked to molecular events for very early detection of pathologies” (PRIMOGAIA) 2019-2023
  • H2020 ATTRACT : “Monitoring tissue implants by field-cycling MRI of quadrupolar-peak contrast agents” (QP-MRI), 2019-2020
  • Compagnia di San Paolo funded project: “Hyperpolarized metabolites for MRI of Cancer” 2017-2020
  • H2020-MSCA-ITN-2017 project: "Zero and Ultra-Low Field Nuclear Magnetic Resonance" (ZULF), 2018-2022
  • H2020 FETOPEN 2018-2020: "Alternatives To Gd", 2019-2023

 

IBFM - Selected publications and grants from last 5 years

  1. Gaglio D, Valtorta S, Ripamonti M, Bonanomi M, Damiani C, Todde S, Negri AS,Sanvito F, Mastroianni F, Di Campli A, Turacchio G, Di Grigoli G, Belloli S,Luini A, Gilardi MC, Colangelo AM, Alberghina L, Moresco RM. Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study. Oncotarget. 2016 Aug 9;7(32):52017-52031.
  2. Valtorta S, Moro M, Prisinzano G, Bertolini G, Tortoreto M, Raccagni I, Pastorino U, Roz L, Sozzi G, Moresco RM. Metabolic Evaluation of Non-Small Cell Lung Cancer Patient-Derived Xenograft Models Using 18F-FDG PET: A Potential Tool for Early Therapy Response. J Nucl Med. 2017 Jan; 58(1):42-47.
  3. Belloli S, Pannese M, Buonsanti C, Maiorino C, Di Grigoli G, Carpinelli A,Monterisi C, Moresco RM, Panina-Bordignon P. Early upregulation of 18-kDatranslocator protein in response to acute neurodegenerative damage in TREM2-deficient mice. Neurobiol Aging. 2017 May;53:159-168.
  4. Rainone P, Riva B, Belloli S, Sudati F, Ripamonti M, Verderio P, Colombo M, Colzani B, Gilardi MC, Moresco RM, Prosperi D. Development of 99mTc-radiolabeled nanosilica for targeted detection of HER2-positive breast cancer. International Journal of Nanomedicine. 2017 May 2; 12: 3447—3461.
  5. Valtorta S, Lo Dico A, Raccagni I, Gaglio D, Belloli S, Politi LS, Martelli C, Diceglie C, Bonanomi M, Ercoli G, Vaira V, Ottobrini L, Moresco RM. Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models. Oncotarget. 2017 Dec 6;8(68):113090-113104.
  6. Corti A, Gasparri AM, Ghitti M, Sacchi A, Sudati F, Fiocchi M, Buttiglione V, Perani L, Gori A, Valtorta S, Moresco RM, Pastorino F, Ponzoni M, Musco G, Curnis F. Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing. Adv Funct Mater. 2017 Sep 26;27(36):1701245.
  7. Belloli S, Zanotti L, Murtaj V, Mazzon C, Di Grigoli G, Monterisi C, Masiello V, Iaccarino L, Cappelli A, Poliani PL, Politi LS, Moresco RM. (18)F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse model of multiple sclerosis. J Neuroinflammation. 2018 Feb 5;15(1):33. IF 5.193
  8. Musazzi L, Sala N, Tornese P, Gallivanone F, Belloli S, Conte A, Di Grigoli G,Chen F, Ikinci A, Treccani G, Bazzini C, Castiglioni I, Nyengaard JR, Wegener G, Moresco RM, Popoli M. Acute Inescapable Stress Rapidly Increases Synaptic Energy Metabolism in Prefrontal Cortex and Alters Working Memory Performance. Cereb Cortex. 2019 Dec 17;29(12):4948-4957. IF 6.308
  9. Murtaj V, Belloli S, Di Grigoli G, Pannese M, Ballarini E, Rodriguez-Menendez V, Marmiroli P, Cappelli A, Masiello V, Monterisi C, Bellelli G, Panina-BordignonP, Moresco RM. Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge. Front Aging Neurosci. 2019 Nov 5;11:299. IF 4.504.
  10. Besusso D, Schellino R, Boido M, Belloli S, Parolisi R, Conforti P, Faedo A; Cernigoj M, Campus I, Laporta A, Dickinson Bocchi V, Murtaj V, Parmar M, Spaiardi P, Talpo F, Maniezzi C, Toselli MG, Biella G, Moresco RM, Vercelli A, Buffo A,*and Cattaneo E. Stem cell derived human striatal progenitors innervate striatal targets and alleviate sensorimotor deficit in a rat model of Huntington Disease. Stem Cell Reports. 2020;14(5):876-891. IF 5.499
  • 2015 PRIN-MIUR “Generation of functional striatal neurons for brain repair in Huntington Disease”. Prot. 2015AY9AYB_003 (2017-2020)
  • 2018 PON-MIUR “MOLIM ONCOBRAIN LAB - “Molecular imaging Innovative methods for the study of tumor and neurodegenerative pathologies” (MOLIM OncoBrain)”, 2018-2021
  • 2017 PRIN-MIUR. Molecular and imaging prodromal markers of dopamine neuron degeneration in animal models of Parkinson’s disease: pathophysiology and clinical perspectives”. Prot. 2017LYTE9M (2019-2022).
  • 2017 EURONANOMED III “New MAGnetic Biomaterials for Brain Repair and Imaging after Stroke - MAGBBRIS” EURONANOMED2017-185 (2018-2021).
  • 2019 AIRC “Effect of metformin as add-on therapy in high grade glioma: identification of imaging biomarker predictive of response”. AIRC: IG 21365 (2019 – 2022).  
  • 2020 FRRBP. “NEVERMIND New frontiers of engineered nanovectors to improve treatment efficacy and safety in neurological disorders”. CP2_16/2018 (2020-2022).
  • 3° Framework agreement Lombardia-CNR: “Metabolic alterations, cellular stress and neurodegenerative processes - AMANDA”. 2016-2019.
  • National project funded by MIUR: “New strategies for diagnostic, therapeutic and clinical care in Neurologic diseases”. 2016-2018.
  • 2017 PRIN-MIUR. “Generation of functional striatal neurons for brain repair in Huntington Disease”. 2017-2019.

 

OSR - Selected publications and grants from last 5 years

  1. Esposito A,  Tacchetti C, et al. “Chest CT-derived pulmonary artery enlargement at the admission predicts overall survival in COVID-19 patients: insight from 1461 consecutive patients in Italy”  Eur Radiol. 2020, 1–11.12 DOI: 10.1007/s00330-020-07622-x
  2. Palmisano, A., Piccoli, M., Monti, C.B., Canu, T., Cirillo, F., Napolitano, A., Perani, L., Signorelli, P., Vignale, D., Anastasia, L., Esposito, A. “Single-shot morpho-functional and structural characterization of the leftventricle in a mouse model of acute ischemia-reperfusion injury with an optimized 3D IntraGate cine FLASH sequence at 7T MR” Magnetic Resonance Imaging 2020, 68, pp. 127-135, DOI: 10.1016/j.mri.2020.01.015  
  3. Palmisano, A., Benedetti, G., Faletti, R., Rancoita, P.M.V., Gatti, M., Peretto, G., Sala, S., Boccia, E., Francone, M., Galea, N., Basso, C., Del Maschio, A., De Cobelli, F., Esposito, A. “Early T1 myocardial MRI mapping: Value in detecting myocardial hyperemia in acute myocarditis” Radiology 2020, 295 (2), pp. 316-325.  DOI: 10.1148/radiol.2020191623 
  4. Esposito, A., Palmisano, A., Barbera, M., Vignale, D., Benedetti, G., Spoladore, R., Ancona, M.B., Giannini, F., Oppizzi, M., Del Maschio, A., De Cobelli, F. “Cardiac Computed Tomography in Troponin-Positive Chest Pain: Sometimes the Answer Lies in the Late Iodine Enhancement or Extracellular Volume Fraction Map” JACC: Cardiovascular Imaging 2020, 12 (4), pp. 745-748.  DOI: 10.1016/j.jcmg.2018.08.013 
  5. Calcinotto, A., Spataro, C., Zagato, E., Di Mitri, D., Gil, V., Crespo, M., De Bernardis, G., Losa, M., Mirenda, M., Pasquini, E., Rinaldi, A., Sumanasuriya, S., Lambros, M.B., Neeb, A., Lucianò, R., Bravi, C.A., NavaRodrigues, D., Dolling, D., Prayer-Galetti, T., Ferreira, A., Briganti, A., Esposito, A., Barry, S., Yuan, W., Sharp, A., De Bono, J., Alimonti, A. “IL-23 secreted by myeloid cells drives castration-resistant prostate cancer” Nature 2018, 559 (7714), pp. 363-369. DOI: 10.1038/s41586-018-0266-0 25 
  6. Mastaglio, S., Genovese, P., Magnani, Z., Ruggiero, E., Landoni, E., Camisa, B., Schiroli, G., Provasi, E., Lombardo, A., Reik, A., Cieri, N., Rocchi, M., Oliveira, G., Escobar, G., Casucci, M., Gentner, B., Spinelli, A., Mondino, A., Bondanza, A., Vago, L., Ponzoni, M., Ciceri, F., Holmes, M.C., Naldini, L., Bonini, C. “NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease” Blood 2017, 130 (5), pp. 606-618.
  7. Dugnani E, Pasquale V, Liberati D, Citro A, Cantarelli E, Pellegrini S, Marra P, Canu T, Balzano G, Scavini M, Esposito A, Doglioni C, Piemonti L. “Modeling the Iatrogenic Pancreatic Cancer Risk After Islet Autotransplantation in Mouse”. Am J Transplant. 2017;17(10):2720-2727
  8. Locafaro, G., Andolfi, G., Russo, F., Cesana, L., Spinelli, A., Camisa, B., Ciceri, F., Lombardo, A., Bondanza, A., Roncarolo, M.G., Gregori, S. “IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism” Molecular Therapy 2017, in Press
  9. Corti A, Gasparri AM, Ghitti M, Sacchi A, Sudati F, Fiocchi M, Buttiglione V, Perani L, Gori A, Valtorta S, Moresco RM, Pastorino F, Ponzoni M, Musco G, Curnis F. “Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing”. Adv Funct Mater. 2017;27(36). pii: 1701245
  10. Curnis F, Dallatomasina A, Bianco M, Gasparri A, Sacchi A, Colombo B, Fiocchi M, Perani L, Venturini M, Tacchetti C, Sen S, Borges R, Dondossola E, Esposito A, Mahata SK, Corti A. “Regulation of tumor growth by circulating full-length chromogranin” A. Oncotarget. 2016;7(45):72716-72732
  • Project funded by MIUR: “New nano-systems for targeted delivery of cytokines to tumor”, 2014-2018
  • National project funded by FISM (Italian Foundation for Multiple Schlerosis) “Direct and indirect role of endogenous neural precursor cells in demyelination and remyelination after cuprizone- induced injury”, 2016-2017
  • National project funded by FISM (Italian Foundation for Multiple Schlerosis) “Role of Jab1 and senescence in the pathogenesis of progressive MS in a mouse model”, 2017-2018
  • National project funded by FISM (Italian Foundation for Multiple Schlerosis): “A translational platform for the development of MRI methods to assess myelin architecture”, 2017-2018
  • Regional project POR-FESR 2014-2020: “Artificial Intelligence – Sars Covid Risk Evaluation (AI – ScoRE)”

 

FTGM - Selected publications and grants from last 5 years 

  1. Aquaro G.D., Perfetti M., Camastra G., Monti L., Dellegrottaglie S., Moro C., Pepe A., Todiere G., Lanzillo C., Scatteia A., Di Roma M., Pontone G., Perazzolo Marra M., Barison A., Di Bella G., on behalf of the Cardiac Magnetic Resonance Working Group of the Italian Society of Cardiology “Cardiac MR With Late Gadolinium Enhancement in Acute Myocarditis With Preserved Systolic Function: ITAMY Study”, Journal of the American College of Cardiology 2017, 70, 1977.
  2. Gabisonia K., Prosdocimo G., Aquaro G.D., Carlucci L., Zentilin L., Secco I., Ali H., Braga L., Gorgodze N., Bernini F., Burchielli S., Collesi C., Zandonà L., Sinagra G., Piacenti M., Zacchigna S., Bussani R., Recchia F.A., Giacca M.  “MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs”, Nature 2019, 569, 418.
  3. Aimo A., Januzzi J.L., Vergaro G.G.V., Ripoli A., Latini R., Masson S., Magnoli M., Anand I.S., Cohn J.N., Tavazzi L., Tognoni G., Gravning J., Ueland T., Nymo S.H., Brunner-La Rocca H.P., Genis A.B., Lupón J., De Boer R.A., Yoshihisa A., Takeishi Y., Egstrup M., Gustafsson I., Gaggin H.K., Eggers K.M., Huber K., Tentzeris I., Tang W.H.W., Grodin J., Passino C., Emdin M. “Prognostic value of high-sensitivity troponin T in chronic heart failure an individual patient data meta-analysis”, Circulation 2018, 137, 286.
  4. Emdin M., Aimo A., Rapezzi C., Fontana M., Perfetto F., Seferović P.M., Barison A., Castiglione V., Vergaro G., Giannoni A., Passino C., Merlini G. “Treatment of cardiac transthyretin amyloidosis: An update”, European Heart Journal 2019, 40, 3699.
  5. Emdin M., Mirizzi G., Giannoni A., Poletti R., Iudice G., Bramanti F., Passino C. “Prognostic Significance of Central Apneas Throughout a 24-Hour Period in Patients With Heart Failure”, Journal of the American College of Cardiology 2017, 70, 1351.
  6. Gimelli A., Liga R., Duce V., Kusch A., Clemente A., Marzullo P. “Accuracy of myocardial perfusion imaging in detecting multivessel coronary artery disease: A cardiac CZT study”, Journal of Nuclear Cardiology 2017, 24, 687.
  7. Aimo A., Migliorini P., Vergaro G., Franzini M., Passino C., Maisel A., Emdin M. “The IL-33/ST2 pathway, inflammation and atherosclerosis: Trigger and target?”, International Journal of Cardiology 2018, 267, 192.
  8. Morelli L., Tartaglia D., Bronzoni J., Palmeri M., Guadagni S., Di Franco G., Gennai A., Bianchini M., Bastiani L., Moglia A., Ferrari V., Fommei E., Pietrabissa A., Di Candio G., Mosca F. “Robotic assisted versus pure laparoscopic surgery of the adrenal glands: a case-control study comparing surgical techniques”, Langenbeck's Archives of Surgery 29016, 401, 999.
  9. Giannoni A., Emdin M., Passino C. “Cheyne-Stokes respiration, chemoreflex, and ticagrelor-related dyspnea”,   New England Journal of Medicine 2017, 375, 1004.
  10. Peretto G., Di Resta C., Perversi J., Forleo C., Maggi L., Politano L., Barison A., Previtali S.C., Carboni N., Brun F., Pegoraro E., D'Amico A., Rodolico C., Magri F., Manzi R.C., Palladino A., Isola F., Gigli L., Mongini T.E., Semplicini C., Calore C., Ricci G., Comi G.P., Ruggiero L., Bertini E., Bonomo P., Nigro G., Resta N., Emdin M., Favale S., Siciliano G., Santoro L., Sinagra G., Limongelli G., Ambrosi A., Ferrari M., Golzio P.G., Bella P.D., Benedetti S., Sala S.    “Cardiac and neuromuscular features of patients with LMNA-related cardiomyopathy”, Annals of Internal Medicine 2019, 171, 458.
  • H2020 (SC1-DTH-2018-1): “Interoperable EHRs at user edge”(InteropEHRate), 2018-ongoing
  • H2020 (MSCA-ITN-2019): “The Medical Digital Twin for Aneurysm Prevention and Treatment” –(MEDITATE), 2019-ongoing
  • Project funded by the Italian Ministry of Health: “Relationship between osteoporosis and cardiovascular risk in patients with thalassemia major”, 2013-ongoing
  • Project funded by the Italian Ministry of Health: “Virtual and Augmented Reality Support for Transcatheter Valve Implantation by using Cardiovascular MRI” , 2013-ongoing
  • Project funded by the Italian Ministry of Health: “Myocardial perfusion imaging with cardiovascular magnetic resonance and hyperpolarized contrast media”, 2016-ongoing
  • Project funded by the Italian Ministry of Health: “Validation of Three-Dimensional Virtual and Printed Models in Children Undergoing Cardiac Surgery for Complex Congenital Heart Diseases and Tracheal Defects: Feasibility, Applications, Cost-Effectiveness, and Exploration of New Techniques” , 2016-ongoing
  • Covid19 call: "Development and implementation of a smartphone application for remote monitoring of cardio-respiratory issues during pandemics” (MYBREATHINGHEART), 2020-ongoing
  • MULTICOVID call: "Evaluation of the multisystemic damage and of the genetic and immunologic predisposition in covid19 patients”, 2020-ongoing.

 

UNIPI - Selected publications and grants from last 5 years (updating in progress)

  1. Ciarrocchi, E., Belcari, N. “Cerenkov luminescence imaging: physics principles and potential applications in biomedical sciences” EJNMMI Physics, 2017, 4 (1), art. no. 14.
  2. Nicola Belcari; Niccolò Camarlinghi; Stefano Ferretti; Patricia Iozzo; Daniele Panetta; Piero A. Salvadori; Giancarlo Sportelli; Alberto Del Guerra “NEMA NU-4 Performance Evaluation of the IRIS PET/CT Preclinical Scanner”, IEEE Transactions on Radiation and Plasma Medical Sciences 2017, Volume: 1, Issue: 4, Pages: 301 - 309
  3. Bisogni, M.G., Attili, A., Battistoni, G., Belcari, N., Camarlinghi, N., Cerello, P., Coli, S., Del Guerra, A., Ferrari, A., Ferrero, V., Fiorina, E., Giraudo, G., Kostara, E., Morrocchi, M., Pennazio, F., Peroni, C., Piliero, M.A., Pirrone, G., Rivetti, A., Rolo, M.D., Rosso, V., Sala, P., Sportelli, G., Wheadon, R. “ INSIDE in-beam positron emission tomography system for particle range monitoring in hadrontherapy” Journal of Medical Imaging 2017, 4 (1), art. no. 011005.
  4. Rosso, V., Belcari, N., Bisogni, M.G., Camarlinghi, N., Cirrone, G.A.P., Collini, F., Cuttone, G., Guerra, A.D., Milluzzo, G., Morrocchi, M., Raffaele, L., Romano, F., Sportelli, G., Zaccaro, E. “ DoPET: An in-treatment monitoring system for proton therapy at 62 MeV” Journal of Instrumentation 2016, 11 (12), art. no. C12029.
  5. Panetta, D., Belcari, N., Tripodi, M., Burchielli, S., Salvadori, P.A., Del Guerra, A. “ Performance evaluation of the CT component of the IRIS PET/CT preclinical tomograph”, Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2016, 805, pp. 135-144.
  6. Vanhove, C., Bankstahl, J.P., Krämer, S.D., Visser, E., Belcari, N., Vandenberghe, S. “Accurate molecular imaging of small animals taking into account animal models, handling, anaesthesia, quality control and imaging system performance”, EJNMMI Physics, 2015, 2 (1), art. no. 31, pp. 1-25.
  7. Ciarrocchi, E., Belcari, N., Del Guerra, A., Cherry, S.R., Lehnert, A., J. Hunter, W.C., McDougald, W., Miyaoka, R.S., Kinahan, P.E. “ Cherenkov luminescence measurements with digital silicon photomultipliers: a feasibility study”, EJNMMI Physics, 2015, 2 (1), art. no. 32, pp. 1-22.
  8. Sportelli, G., Belcari, N., Camarlinghi, N., Cirrone, G.A.P., Cuttone, G., Ferretti, S., Kraan, A., Ortuño, J.E., Romano, F., Santos, A., Straub, K., Tramontana, A., Guerra, A.D., Rosso, V. “First full-beam PET acquisitions in proton therapy with a modular dual-head dedicated system”, Physics in Medicine and Biology, 2015, 59 (1), pp. 43-60.
  9. Cecchetti, M., Moehrs, S., Belcari, N., Guerra, A.D. “ Accurate and efficient modeling of the detector response in small animal multi-head PET systems”, Physics in Medicine and Biology 2013, 58 (19), pp. 6713-6731.
  10. Pagliazzi, M., Ciarrocchi, E., Del Guerra, A., Belcari, N., Boschi, F., Spinelli, A.E. “ Development of a simulation environment for Cerenkov luminescence imaging” IEEE Nuclear Science Symposium Conference Record, 2013, art. no. 6829367.
  • FP7-COOPERATION. FP7-HEALTH-2013-INNOVATION-1: “A dedicated trimodality (PET/MR/EEG) imaging tool for schizophrenia (TRIMAGE)”, 2014-2018
  • EC/Regione Toscana, ERANET-COFUND PhotonicSensing” Ultra-Time-Of-Flight Positron Emission Tomography with multi-channel digital Silicon photomultipliers and photonic crystals (UTOFPET)”, 2018-2020
  • Project funded by Inviscan s.a.s.: “Development of the pre-clinical imaging system IRIS PET/CT”, 2013-running

 

IFC - Selected publications and grants from last 5 years (updating in progress)

  1. F. Ratto, S. Centi, C. Avigo, C. Borri, F. Tatini, L. Cavigli, C. Kusmic, B. Lelli, S. Lai, M. Benagiano, M. M. D'Elios, S. Colagrande, F. Faita, L. Menichetti, R. Pini A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging. Advanced Functional Materials, 26(39):7178-7185; ERRATA CORRIGE: F. Ratto, S. Centi, C. Avigo, C. Borri, F. Tatini, L. Cavigli, C. Kusmic, B. Lelli, S. Lai, M. Benagiano, M. M. D'Elios, S. Colagrande, F. Faita, L. Menichetti, R. Pini, A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging. Advanced Functional Materials, 26(44):7954
  2. N. Di Lascio, C. Kusmic, F. Stea, F. Lenzarini, C. Barsanti, A. Leloup, F. Faita, Longitudinal micro-ultrasound assessment of the ob/ob mouse model: Evaluation of cardiovascular, renal and hepatic parameters, International journal of obesity, doi:10.1038/ijo.2017.219
  3. Luchini, A., Irace, C., Santamaria, R., Montesarchio, D., Heenan, R.K., Szekely, N., Flori, A., Menichetti, L., Paduano, L. Phosphocholine-decorated superparamagnetic iron oxide nanoparticles: Defining the structure and probing: In vivo applications (2016) Nanoscale, 8 (19), pp. 10078-10086.
  4. Panetta D, Belcari N, Tripodi M, Burchielli S, Salvadori PA, Del Guerra A. Performance evaluation of the CT component of the IRIS PET/CT preclinical tomograph. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2016;805:135-44.
  5. Belcari N, Camarlinghi N, Panetta D, Iozzo P, Burchielli S, Salvadori PA, et al. Multimodal 4D cardiac imaging with the preclinical IRIS PET/CT scanner. European Journal of Nuclear Medicine and Molecular Imaging. 2016;43:S514-S.
  6. Camarlinghi N, Luongo C, Belcari N, Panetta D, Iozzo P, Burchielli S, et al. Performance evaluation of the step and shoot acquisition modality of the IRIS PET scanner. European Journal of Nuclear Medicine and Molecular Imaging. 2016;43:S503-S.
  7. Guzzardi MA, Liistro T, Gargani L, Ait Ali L, D'Angelo G, Rocchiccioli S, La Rosa F, Kemeny A, Sanguinetti E, Ucciferri N, De Simone M, Bartoli A, Festa P, Salvadori PA, Burchielli S, Sicari R, Iozzo P. Maternal Obesity and Cardiac Development in the Offspring: Study in Human Neonates and Minipigs. JACC Cardiovasc Imaging. 2017 Nov 10. pii: S1936-878X(17)30906-3.
  8. Gastaldelli A, Gaggini M, Daniele G, Ciociaro D, Cersosimo E, Tripathy D, Triplitt C, Fox P, Musi N, DeFronzo R, Iozzo P. Exenatide improves both hepatic and adipose tissue insulin resistance: A dynamic positron emission tomography study. Hepatology. 2016 Dec;64(6):2028-2037.
  9. Guzzardi MA, Iozzo P, Salonen MK, Kajantie E, Eriksson JG. Maternal adiposity  and infancy growth predict later telomere length: a longitudinal cohort study. Int J Obes (Lond). 2016 Jul;40(7):1063-9.
  10. Sanguinetti E, Liistro T, Mainardi M, Pardini S, Salvadori PA, Vannucci A, Burchielli S, Iozzo P. Maternal high-fat feeding leads to alterations of brain glucose metabolism in the offspring: positron emission tomography study in a porcine model. Diabetologia. 2016 Apr;59(4):813-21
 

SDN - Selected publications and grants from last 5 years

  1. Catalano OA, Lee SI, Parente C, Cauley C, Furtado FS, Striar R, Soricelli A, Salvatore M, Li Y, Umutlu L, Cañamaque LG, Groshar D, Mahmood U, Blaszkowsky LS, Ryan DP, Clark JW, Wo J, Hong TS, Kunitake H, Bordeianou L, Berger D, Ricciardi R, Rosen B, “Improving staging of rectal cancer in the pelvis: the role of PET/MRI”, Eur J Nucl Med Mol Imaging. 2020 Oct 9. doi: 10.1007/s00259-020-05036-x.
  2. Aiello M, Alfano V, Salvatore E, Cavaliere C, Picardi M, Della Pepa R, Nicolai E, Soricelli A, Vella A, Salvatore M, Mascalchi M, “[18F]FDG uptake of the normal spinal cord in PET/MR imaging: comparison with PET/CT imaging”, EJNMMI Res. 2020 Aug 6;10(1):91. doi: 10.1186/s13550-020-00680-8.
  3. Schiano C, Franzese M, Pane K, Garbino N, Soricelli A, Salvatore M, de Nigris F, Napoli C., “Hybrid 18F-FDG-PET/MRI Measurement of Standardized Uptake Value Coupled with Yin Yang 1 Signature in Metastatic Breast Cancer. A Preliminary Study”, Cancers (Basel). 2019 Sep 26;11(10):1444. doi: 10.3390/cancers11101444.
  4. Borrelli P, Cavaliere C, Basso L, Soricelli A, Salvatore M, Aiello M., “ Diffusion Tensor Imaging of the Kidney: Design and Evaluation of a Reliable Processing Pipeline.”, Sci Rep. 2019 Sep 4;9(1):12789. doi: 10.1038/s41598-019-49170-5.
  5. Longarzo M, Cavaliere C, Orsini M, Tramontano L, Aiello M, Salvatore M, Grossi D., “A Multimodal Imaging Study in a Case of Bilateral Thalamic Damage With Multidomain Cognitive Impairment.”, Front Neurol. 2019 Oct 14;10:1048. doi: 10.3389/fneur.2019.01048.
  6. Inglese M, Cavaliere C, Monti S, Forte E, Incoronato M, Nicolai E, Salvatore M, Aiello M., “A multi-parametric PET/MRI study of breast cancer: Evaluation of DCE-MRI pharmacokinetic models and correlation with diffusion and functional parameters”, NMR Biomed. 2019 Jan;32(1):e4026. doi: 10.1002/nbm.4026.
  7. Incoronato M, Grimaldi AM, Cavaliere C, Inglese M, Mirabelli P, Monti S, Ferbo U, Nicolai E, Soricelli A, Catalano OA, Aiello M, Salvatore M., “Relationship between functional imaging and immunohistochemical markers and prediction of breast cancer subtype: a PET/MRI study”, Eur J Nucl Med Mol Imaging. 2018 Sep;45(10):1680-1693. doi: 10.1007/s00259-018-4010-7.
  8. Romeo V, Iorio B, Mesolella M, Ugga L, Verde F, Nicolai E, Covello M.,” Simultaneous PET/MRI in assessing the response to chemo/radiotherapy in head and neck carcinoma: initial experience”, Med Oncol. 2018 Jun 19;35(7):112. doi: 10.1007/s12032-018-1170-z.
  9. Cavaliere C, Kandeepan S, Aiello M, Ribeiro de Paula D, Marchitelli R, Fiorenza S, Orsini M, Trojano L, Masotta O, St Lawrence K, Loreto V, Chronik BA, Nicolai E, Soddu A, Estraneo A., “Multimodal Neuroimaging Approach to Variability of Functional Connectivity in Disorders of Consciousness: A PET/MRI Pilot Study”, Front Neurol. 2018 Oct 18;9:861. doi: 10.3389/fneur.2018.00861.
  10. Marchitelli R, Aiello M, Cachia A, Quarantelli M, Cavaliere C, Postiglione A, Tedeschi G, Montella P, Milan G, Salvatore M, Salvatore E, Baron JC, Pappatà S., “Simultaneous resting-state FDG-PET/fMRI in Alzheimer Disease: Relationship between glucose metabolism and intrinsic activity”, Neuroimage. 2018 Aug 1;176:246-258. doi: 10.1016/j.neuroimage.2018.04.048.
  • MISE Project “Grandi progetti R&S”: ““Big Data” and genomic imaging for the development of biomarkers and nanovectorial innovative drugs for diagnosis and therapy of inflammatory processes in dementia” (BIGIMAGING)
  • PON_MIUR RI 2014-2020 - "Personalized medicine for innovative strategies in neuropsichiatric and vascular diseases” (PERMEDNET)
  • PON_MIUR RI 2014-2020 - “Molecular imaging Innovative methods for the study of tumor and neurodegenerative pathologies” (MOLIM OncoBrain)
  • POR CAMPANIA FESR 2014-2020 - “Diagnostic and therapeutic innovations for neuroendocrine and endocrine tumors and for glioblastoma through an integrated technological platform of clinical, genomic, ICT, pharmaceutical and pharmacological competences” (RAREPLATNET)
  • PON "R&C" 2007-2013 - "High efficiency Diagnostic methodologies for the osteo-articular patient: dedicated MRI for non invasive pre- and post-surgical imaging in the implanation of prosthesis and integrated systems helping the management of the clinical/diagnostic data” (MEDIA)
  • Project funded by Regione Campania - “Very low dose Chest CT protocols and artificial intelligence techniques for early diagnosis and quantification of COVID-19 disease”

 

IBB - Selected publications and grants from last 5 years

  1. Gargiulo S, Anzilotti S, Coda AR, Gramanzini M, Greco A, Panico M, Vinciguerra A, Zannetti A, Vicidomini C, Dollé F, Pignataro G, Quarantelli M, Annunziato L, Brunetti A, Salvatore M, Pappatà S. Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with 18F-DPA-714 and micro-PET/CT. Eur J Nucl Med Mol Imaging. 2016, 43 (7): 1348-59
  2. Auletta L, Greco A, Albanese S, Meomartino L, Salvatore M, Mancini M. Original Research: Feasibility and safety of two surgical techniques for the development of an animal model of jugular vein occlusion. Exp Biol Med, 2017 Jan; 242(1): 22-28.
  3. Camorani S, Hill BS, Fontanella R, Greco A, Gramanzini M, Auletta L, Gargiulo S, Albanese S, Lucarelli E, Cerchia L, Zannetti A. Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRbeta Aptamer. Theranostics, 2017 Aug 22; 7(14): 3595-3607.
  4. Gargiulo S, Coda AR, Panico M, Gramanzini M, Moresco RM, Chalon S, Pappata S. Molecular imaging of neuroinflammation in preclinical rodent models using positron emission tomography. Q J Nucl Med Mol Im, 2017 Mar; 61(1): 60-75.
  5. Albanese S, Greco A, Auletta L, Mancini M. Mouse models of neurodegenerative disease: preclinical imaging and neurovascular component. Brain Imaging Behav, 2017 Oct 26; N/D: N/D-N/D.
  6. Torino E, Auletta L, Vecchione D, Orlandella FM, Salvatore G, Iaccino E, Fiorenza D, Grimaldi AM, Sandomenico A, Albanese S, Sarnataro D, Gramanzini M, Palmieri C, Scala G, Quinto I, Netti PA, Salvatore M, Greco A. Multimodal imaging for a theranostic approach in a murine model of B-cell lymphoma with engineered nanoparticles, 2017 Nov 22; 14(2): 483-491.
  7. Greco A, Zannetti A, Pappata S, Albanese S, Coda AR, Ragucci M, Nardelli A, Brunetti A, Cuocolo A, Salvatore M. Measurement of [123I]FP-CIT binding to the dopamine transporter (DAT) in healthy mouse striatum using dedicated small animal SPECT imaging: feasibility, optimization and validation. Q J Nucl Med Mol Im, 2018 Mar; 62(1): 112-117.
  8. Gargiulo S, Albanese S, Mancini M. State of the art preclinical photoacoustic imaging: recent advances in cancer theranostics. Contrast Media & Molecular Imaging, 2019; 2019: Article-Article.
  9. Iommelli F, De Rosa V, Terlizzi C, Fonti R, Del Vecchio S. Preclinical Imaging in Targeted Cancer Therapies. Semin Nucl Med, 2019 Sep; 49(5): 369-381.
  10. Coda AR, Anzilotti S, Boscia F, Greco A, Panico M, Gargiulo S, Gramanzini M, Zannetti A, Albanese S, Pignataro G, Annunziato L, Salvatore M, Brunetti A, De Berardinis P, Quarantelli M, Palma G, Pappata S. In vivo imaging of CNS microglial activation/macrophage infiltration with combined [(18)F]DPA-714-PET and SPIO-MRI in a mouse model of relapsing remitting experimental autoimmune encephalomyelitis. Eur J Nucl Med Mol Imaging , 2020 May 7; N/D: N/D-N/D
  • National PRIN project “Toward the development of novel biomarkers to evaluate experimental therapies for Inherited Retinal Dystrophies: correlation between Magnetic Resonance Imaging and visual function”, 2019-2022
  • National PRIN project “Theranostic nanoparticles-based approach targeting a set of microRNAs in drug resistant thyroid and breast cancers”, 2019-2022
  • PON MOLIM ONCOBRAIN “Molecular imaging Innovative methods for the study of tumor and neurodegenerative pathologies” (MOLIM OncoBrain)”, 2018-2021
  • POR EMORFORAD “Development of an integrated radiomic and phenotypic system for the diagnosis, prognosis and personalization of head and neck tumors”, 2018-2021
  • National PRIN project “Lab on fIber technology For advanced optical nanoprobEs (LIFE)”, 2016-2018.
  • National PRIN project “Regenerative potential of extracellular vesicles-derived from mesenchymal stem cells on epithelial wound healing”, 2016-2018.
  • National F.I.R.S.T. SIR project: “Learning from diabetes to treat Alzheimer's disease: a role for HSP60 in the regulation of brain IGF-I receptor signaling”, 2015-2018.

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